Introduction Cellular senescence is a stress-response state in which a cell stops dividing for the long term but remains alive ...
Introduction Metformin is a prescription medicine with a long-established role in type 2 diabetes. Its established medical purpose is improving ...
Introduction Spermidine is a natural molecule made by human cells and also obtained from food. It belongs to a family ...
Introduction Alpha-ketoglutarate (AKG), also called 2-oxoglutarate, is a normal molecule in the tricarboxylic-acid cycle, or TCA cycle—the mitochondrial network that ...
Introduction Rapamycin, also called sirolimus, is a prescription medicine that inhibits part of the mechanistic target of rapamycin pathway. The ...
Introduction Butyrate is a short-chain fatty acid produced naturally when intestinal microorganisms ferment certain carbohydrates that reach the colon. Sodium ...
Introduction NAD⁺, short for nicotinamide adenine dinucleotide, is a molecule required for ordinary cellular metabolism. Cells also consume NAD⁺ when ...
Introduction Partial cellular reprogramming is an experimental approach intended to shift an older or damaged cell towards a younger regulatory ...
Introduction Epigenetic engineering of ageing is the deliberate attempt to alter the regulatory systems that determine which genes a cell ...
Introduction Age-related frailty is a geriatric syndrome in which physiological reserve is reduced, increasing vulnerability to illness, surgery, medication effects ...
